个人简介：
吴国火，男，2022年12月获得安徽农业大学博士学位，现为阜阳师范大学生物与食品工程学院讲师，硕士生导师。主要研究方向为天然食品及食药同源类物质中功能因子提取、鉴定及其构效关系解析，功能性食品研究开发等，在Phytomedicine, Food Science and Human Wellness及Journal of Nutritional Biochemistry等国际权威期刊发表高水平SCI论文10余篇，近五年主持或参与各类课题10余项。
教育背景：
2019.09-2022.12安徽农业大学茶学专业农学博士
2016.09-2019.06中国计量大学生物化学与分子生物学专业理学硕士
2012.09-2016.06中国计量大学动植物检疫专业理学学士
工作经历：
2023.05-至今阜阳师范大学生物与食品工程学院讲师
科研项目：
1.安徽省高等学校科学研究重点项目（2024AH051472)（主持）；
2.阜阳师范大学高层次人才引进项目（2023KYQD0022）（主持）；
3.阜阳师范大学与阜阳市中医医院能力提升计划项目（2024FYNU-TCMH05）（共同主持）；
4.安徽省高校研究生科学研究项目（YJS20210210）（主持）；
5.国家自然科学基金区域创新发展联合基金重点支持项目（U19A2034）（参与）；
6.安徽高校协同创新项目（GXXT-2019-049）（参与）。
代表性论文：
1. Guohuo Wu#, Shuolei Xu#, Zhaoyun Chen#, Li Wu, Wenli Fan, Xiaoyun Wu, Mengyu Li, Changqing Qu, Yuntao Ji*.Comparative analysis of metabolite signatures and hypoglycemic effects in Toona sinensis leaves processed by two distinct methods[J].Food Chemistry: X. 2025, 29, 102821.
2. Guohuo Wu#, Zhaoyun Chen#, Yan Tang, Shuolei Xu, Wenli Fan, Li Wu, Yuntao Ji, Changqing Qu*.Comparative Effects of Maturity and Processing on Chemical Composition and Bioactivities in Toona sinensis Leaves [J]. Foods. 2025, 14, 2717.
3. Guohuo Wu#, Mengdi Wang#, Zhaofeng Du, Zhuang Li, Tingting Han, Zhongwen Xie*, Wei Gu*. Tea polyphenol EGCG enhances the improvements of calorie restriction on hepatic steatosis and obesity while reducing its adverse outcomes in obese rats[J]. Phytomedicine, 2025, 141, 156744.
4. Wei Gu#，Zhutong Wang#，Guohuo Wu，Huimin Guo，Huijun Cheng，Cong Li，Linbo Chen，Daxiang Li*，Zhongwen Xie*．Distinct Effects of Three Tea Varieties Made Green Teas on Improving Diabetic Dyslipidemia Induced by High-Fat Diet in C57BL/6J Mice [J]. Food Science and Human Wellness. 2025, 14(11), 9250271.
5. Guohuo Wu#, Tingting Han#, Mengdi Wang, Zhaofeng Du, Zhongwen Xie*, Wei Gu*. L-theanine enhances the improvements of EGCG on glucose and lipid metabolism disorders in obese rats[J]. Journal of Functional Foods. 2024, 123, 106580.
6. Zhaofeng Du#, Guohuo Wu#, Huijun Cheng, Tingting Han, Daxiang Li, Zhongwen Xie*. L-Theanine Ameliorates Obesity-Related Complications Induced by High-Fat Diet in Mice: Insights from Transcriptomics and Metabolomics. Foods. 2024, 13, 2977.
7. Wei Gu#, Guohuo Wu#, Guijie Chen, Xianghui Meng, Zhongwen Xie*, Shanbao Cai*. Polyphenols alleviate metabolic disorders: the role of ubiquitin-proteasome system[J]. Frontiers in Nutrition. 2024, 11, 1445080.
8. Guohuo Wu, Huijun Cheng, Huimin Guo, Zhuang Li, Daxiang Li*, Zhongwen Xie*. Tea Polyphenol EGCG Ameliorates Obesity-related Complications by Regulating Lipidomic Pathway in Leptin Receptor Knockout Rats[J]. Journal of Nutritional Biochemistry. 2023, 118, 109349.
9. Guohuo Wu#, Wei Gu#, Guijie Chen#, Huijun Cheng, Daxiang Li*, Zhongwen Xie*. Interactions of Tea Polysaccharides with Gut Microbiota and Their Health-promoting Effects to Host: Advances and Perspectives[J]. Journal of Functional Foods. 2023, 102, 105468.
10. Guohuo Wu, Wei Gu, Huijun Cheng, Huimin Guo, Daxiang Li*, Zhongwen Xie*. Huangshan Maofeng Green Tea Extracts Prevent Obesity-Associated Metabolic Disorders by Maintaining Homeostasis of Gut Microbiota and Hepatic Lipid Classes in Leptin Receptor Knockout Rats[J]. Foods. 2022, 11, 2939.
11. Guohuo Wu, Xiaoyun Sun, Huijun Cheng, Shan Xu, Daxiang Li*, Zhongwen Xie*. Large Yellow Tea Extract Ameliorates Metabolic Syndrome by Suppressing Lipogenesis through SIRT6/SREBP1 Pathway and Modulating Microbiota in Leptin Receptor Knockout Rats[J]. Foods. 2022, 11(1), 1638.
12. Huijun Cheng, Zenghui Liu, Guohuo Wu, Chi-Tang Ho, Daxiang Li, Zhongwen Xie*. Dietary compounds regulating the mammal peripheral circadian rhythms and modulating metabolic outcomes[J]. Journal of Functional Foods. 2021, 78(1):104370.
13.吴国火,崔林,王梦馨,李红亮,韩宝瑜*.茶树花香气及茶叶气味对中华蜜蜂的引诱效应[J].生态学报, 2020, 40(12): 4024-4031.（一级期刊，CSCD收录）
14.王梦馨,吴国火,崔林,韩宝瑜*.茶树花Cu/Zn-SOD酶活性及其基因表达分析[J].热带作物学报, 2020, 41(6): 1167-1173.（核心期刊，CSCD收录）
15.俞鹏飞,吴国火,韩宝瑜*.白边大叶蝉线粒体基因组测序与分析[J].安徽农业大学学报, 2017, 44(5):874-881.（核心期刊，CSCD收录）
教学工作：
主讲课程包括《食品毒理学》、《食品安全监督管理》和《基因工程原理》等。指导学生获得安徽省大学生生命科学竞赛、食品设计创新大赛等多个奖项；获批省级大学生创新创业训练计划项目1项。主持校级教学研究重点项目（2025JYXM0009）1项。
社会工作：
安徽省实验动物学会会员、安徽省园艺学会会员
