个人简介：
刘祥，男，1983年生，教授，博士，硕士生导师，中山大学生化与分子专业博士，西北农林科技大学兽医学博士后，德国柏林自由大学访学，安徽省乡村振兴协同技术服务中心（阜阳师大）执行副主任，安徽省生物化学与分子生物学学会理事，主要从事动物疫苗、药物制剂研究。主持科技部高端外国专家项目1项，主持省科技厅重点研发、面上项目各1项，主持安徽省高校协同创新项目1项，主持教育厅项目3项、校级项目4项、横向项目2项。参与国家高技术研究发展(863)计划、国家自然科学基金、国家高端外专局项目、陕西省科技厅重点研发、陕西省科技创新团队等项目8项。以第一作者/通讯作者在J Proteome Res、Vaccines、Fish Shellfish Immun、Int J Mol Sci等国内外知名期刊上发表论文50余篇（SCI收录29篇）。Vaccines、Appl Microbiol Biot、Int J Biol Macromol、J Med Food、J Cell Biochem等期刊审稿人。申请国家发明专利3项，参与出版专著2部；获校级优秀硕士生导师、优秀科技工作者、优秀本科生指导教师、优秀班主任称号，校讲课大赛二等奖。指导研究生获国家奖学金3人次，省级优秀毕业生、校优秀毕业论文各1次；指导本科生获国家级大学生创新创业项目1项、省级3项，指导本科生获“大学生挑战杯科技论文竞赛”省二等奖1次。
一、承担主要的科研项目：
1. 2023年安徽省高校协同创新项目：绿色无抗养殖OmpA蛋白免疫制剂的生物合成与开发利用（GXXT-2023-077），主持，100万元，在研。
2. 2021年省科技厅自然科学基金面上项目：基于表位疫苗技术的奶山羊乳房炎多价疫苗的合成及免疫机制研究（2022JM-120），主持，5万元，已结题。
3. 2022年省教育厅重点项目：基于表位疫苗技术的奶山羊乳腺炎多价疫苗设计重塑、生物合成与免疫活性研究（2022AH051330），主持，10万元，已结题。
4. 2018年科技部国家外国专家局项目：秦岭特色生物资源开发利用关键技术研究与示范（GDT20186100426），主持，32万元，已结题。
5. 2016年省科技厅重点研发项目：奶牛乳房炎三联重组表位多肽疫苗的研发（2016NY-088），主持，15万元，已结题。
6. 2017年省教育厅科学研究计划项目：奶牛乳房炎三联表位多肽疫苗的研制及免疫保护功能研究（17JK0137），主持，3万元，已结题。
7. 2021年市校合作项目：秦巴中药在水产养殖病原菌防治中的应用及其免疫机制研究（SXJ-2104），主持，20万元，已结题。
8. 2013年省教育厅科学研究计划项目：骨硬化蛋白在股骨头坏死症中的作用研究（2013JK0723），主持，2万元，已结题。
二、代表性的科研论文：
1. Xiao Huihui, Duan Saixing, Cui Pan, Chen Jing, Che Xixian, Lu Juan, Wang Juan, Zhu Guoping, Liu Yong*,Liu Xiang*. Polyvalent immunoprotection of protein, DNA and IgY antibody vaccines ofVibrio fluvialisouter membrane protein VF08100 in fish. Fish and Shellfish Immunology, 2025, 161: 110260. (中科院SCI二区Top，通讯作者)
2. Xiao Huihui, Cui Pan, Chen Jing, Meng Libing, Che Xixian, Ma Zijian, Wu Xiaoqing, Lu Juan, Sun Shujun, Zhu Gguoping, Liu Yong*,Liu Xiang*. Evaluation of the multivalent immune protective effects of theVibrio fluvialisouter membrane protein VF17320, and its DNA and IgY antibody vaccines in fish. Frontiers in Veterinary Science, 2025, 12:1586258. (中科院SCI二区，通讯作者)
3. Sun Shujun, Chen Jing, Cui Pan, Yang Xiaoxiao, Zheng Yuhan, Ma Zijian, Liu Yong,Liu Xiang*. Evaluation of immunoprotective activities of white button mushroom (Agaricus bisporus) water Extract against major pathogenic bacteria (Aeromonas hydrophilaorVibrio fluvialis) in goldfish (Carassius auratus). Animals, 2025, 15: 2257. (中科院SCI二区，通讯作者)
4. Xiao Huihui, Chen Jing, Cui Pan, Che Xixian, Wu Xiaoqing, Lu Juan, Zhu Guoping, Liu Yong*,Liu Xiang*. Evaluation of the multivalent immunoprotective effects of protein, DNA, and IgY vaccines against Vibrio fluvialis outer membrane protein VF14355 in Carassius auratus. International Journal of Molecular Sciences, 2025, 26: 3379. (中科院SCI三区，通讯作者)
5. Chen Jing, Cui Pan, Xiao Huihui, Wu Xiaoqing, Lu Juan, Liu Yong*,Liu Xiang*. The passive immunoprotective activity using egg yolk IgY antibodies of live or inactivatedAeromonas veroniiagainst major pathogenic bacteria (A. veroniiandA. hydrophila) in fish. Veterinary Science, 2025, 12: 831. (中科院SCI三区，通讯作者)
6. Chen Jing, Cui Pan, Xiao Huihui, Han Xiaohui, Ma Ziye, Wu Xiaoqing, Lu Juan, Zhu Guoping, Liu Yong,Liu Xiang*. Multivalent immune-protective effects of egg yolk immunoglobulin Y (IgY) derived from live or inactivatedShewanella xiamenensisagainst major aquaculture pathogens. International Journal of Molecular Sciences, 2025, 26: 7012. (中科院SCI三区，通讯作者)
7. Cui Pan, Chen Jing,Liu Xiang*. Assessment of egg yolk IgY antibodies against live or inactivatedAeromonas hydrophilafor polyvalent passive immunization in goldfish (Carassius auratus). Fishes, 2025, 10, 491.（中科院SCI三区，通讯作者）
8.Liu Xiang, Nie Yuhao, Wang Beibei, et al. Evaluation of α-glucosidase, α-amylase and lipase inhibitory activities of dietary plant foods. Journal of Food Science and Technology, 2025, 10: 24-28. (中科院SCI四区)
9.Liu Xiang, Xiao Huihui, Cui Pan, Chen Jing, Chao Jia, Wu Xiaoqing, Lu Juan, Zhang Xiaoying, Xu Gaoxiao, Liu Yong*. Differential polyvalent passive immune protection of egg yolk antibodies (IgY) against live and inactivatedVibrio fluvialisin fish. Fish and Shellfish Immunology, 2024, 151: 109751. (中科院SCI二区Top)
10.Liu, Xiang, Chao Jia, Xiao Huihui, Chen Jing, Cui Pan, Wu Xiaoqing, Lu Juan, Wang Juan, Chen Chunlin, Zhang Xiaoying, Xu Gaoxiao, Liu Yong*. Identification of polyvalent passive vaccine candidates from egg yolk antibodies (IgY) of important outer membrane proteins ofAeromonas hydrophilain fish. Aquaculture Reports, 2024, 35: 102002. (中科院SCI二区Top)
11.Liu Xiang, Li Hui, Peng Xuanxian.Escherichia coliactivate extraintestinal antibody response and provide anti-infective immunity. International Journal of Medical Sciences, 2024, 25, 7450.（中科院SCI二区）
12. Xiao Huihui, Cui Pan, Chen Jing, Han Xiaohui, Ma Ziye, Chen Chen, Liu Yong*,Liu Xiang*. A comparison of polyvalent passive immunoprotection from antibodies with different immunity models of live or inactivatedVibrio fluvialisin Fish. Fishes, 2024, 9: 302. (中科院SCI三区)
13. Jian Sijie, SunWei, ...Liu Xiang*. The immune response and passive protective abilities of the outer membrane lipoprotein Slp ofAeromonas hydrophilaagainst the major pathogenic bacteria of freshwater aquaculture in fish. Pakistan J Zool, 2024, 56(2): 889-877 (中科院SCI四区,通讯作者)
14.Liu Xiang, Xiao Huihui, Chao Jia, Jian Sijie, Wu Xiaoqing, Lu Juan, Wang Juan, Chen Chunlin, Liu Yong*. Polyvalent passive vaccine candidates from egg yolk antibodies (IgY) of important outer membrane proteins (PF1380 and ExbB) ofPseudomonas fluorescensin fish. Fish and Shellfish Immunology, 2023, 143: 109211. (中科院SCI二区Top)
15.Liu Xiang, Nie Yuhao, Chen Rui, et al. Inhibitory activities of extracts from Chinese medicinal herbs on α-amylase, α-glucosidase, and pancreatic lipase. Pharmacognosy Magazine, 2023, 19(3): 530-538. (中科院SCI四区)
16.Liu Xiang, Rong Na, Sun Wei, et al. The identification of polyvalent protective immunogens and immune abilities from the outer membrane proteins ofAeromonas hydrophilain fish. Fish & Shellfifish Immunology, 2022, 128: 101-122.（中科院SCI二区Top）
17.Liu Xiang, Sun Wei, Jian Sijie, et al. Passive protective ability of the outer membrane protein PF1380 ofPseudomonas fluorescensagainst the major pathogenic bacteria of freshwater aquaculture in fish. Aquaculture Reports, 2022, 22: 100985.（中科院SCI二区Top）
18.Liu Xiang, Sun Wei, Jian Sijie, et al. Synthesis ofEscherichia coliOmpA oral nanoparticles and evaluation of immune functions against the major etiologic agent of cow mastitis. Vaccines, 2021, 9: 304.（中科院SCI二区）
19. Sun Wei, Rong Na, Jian Sijie, Kang Chao, Chen Chunlin, Chen Rui, Ding Rui, Chen Chen,Liu Xiang*. Immune responses and protective efficacy of outer membrane protein ExbB ofPseudomonas fuorescensagainstAeromonas hydrophilaandPseudomonas fuorescensaffectingCarassius auratus. Aquaculture International, 2021, 29:2823-2840.（中科院SCI三区）
20.Liu Xiang, Chen Chen, Zhang Xiaoying. Drug–drug interaction of acetaminophen and roxithromycin with the cocktail of cytochrome P450 and hepatotoxicity in rats. International Journal of Medical Sciences, 2020, 17: 414-421.（中科院SCI三区）
21. Xu Long,Liu Xiang*, Chen Chen, et al. Determination of dehydroepiandrosterone in dietary supplements and pharmaceutical products by a competitive chemiluminescent enzyme immunoassay. Analytical Letters, 2020, 3: 842-853. (中科院SCI四区,通讯作者)
22. Chen Chen, …Liu Xiang*, Zhang Xiaoying. Immunoprotective evaluation ofEscherichia coliouter membrane protein A against the main pathogens of animal mastitis. Tropical Journal of Pharmaceutical Research January, 2020, 19 (1): 155-162. (中科院SCI四区)
23. Chen Chen, …Liu Xiang*, Zhang Xiaoying*. Purification and characterization of lysozyme from Chinese Lueyang black-bone Silky fowl egg white. Preparative Biochemistry & Biotechnology, 2019, 49(3): 215-221. (中科院SCI四区,通讯作者)
24. Chen Chen, …Zhang Xiaoying,Liu Xiang*. Evaluation of immunogenicity, protective immunity on aquaculture pathogenic Vibrio and fermentation ofVibrio alginolyticusflagellin FlaC protein. Iranian Journal of Biotechnology, 2019, 17(3): e2628. (中科院SCI四区,通讯作者)
25.Liu Xiang, Yang Manjun, Wang Shengnan, et al. Difffferential antibody responses to outer membrane proteins contribute to difffferential immune protections between live and inactivatedVibrio parahemolyticus. Journal of Proteome Research, 2018, 17: 2987-2994.（中科院SCI二区）
26. Chen Chen, …Zhang Xiaoying,Liu Xiang*. Purification and characterization of an antimicrobial protein fromGastrodia elata Blumetubers. Tropical Journal of Pharmaceutical Research September, 2018, 17(9): 1717-1723. (中科院SCI四区,通讯作者)
27.Liu Xiang, Chen Chunlin, Chen Chen, et al. Construction of a recombinant OmpC dominant epitope based vaccine againstEscherichia coli and evaluation of its immunogenicity and protective immunity. Jundishapur Journal of Microbiology, 2017, 10(11):e55652. (中科院SCI四区)
28.Liu Xiang, Chen Chunlin, Chen Chen, et al. Construction and evaluation of a novel triple cell epitope based polypeptide vaccine against cow mastitis induced byStaphylococcus aureus,Escherichia coliandStreptococcus. Tropical Journal of Pharmaceutical Research, 2017, 16 (10): 2477-2486. (中科院SCI四区)
29.Liu Xiang, She Xintao, Zhu Qingfeng, et al. Heterogeneous interactome betweenLitopenaeus vannameiplasma proteins andVibrio parahaemolyticusouter membrane proteins. Fish & Shellfifish Immunology, 2013, 34: 192-198.（中科院SCI一区Top）
中文期刊：以第一作者/通讯作者，发表中文核心论文30余篇。
